Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMF8W8F)

Drug Name

SAR443579 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Acute myeloid leukaemia	2A60	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cell division cycle protein 123 (CDC123)	TT3PRUG	CD123_HUMAN	Not Available	[2]
Natural cytotoxic triggering receptor 1 (NCR1)	TTQNRJM	NCTR1_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT05086315) An Open-label, First-in-human, Dose-escalation/Expansion Study of SAR443579 Administered as Single Agent by Intravenous Infusion in Adult and Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (R/R AML), B-cell Acute Lymphoblastic Leukemia (B-ALL), High Risk-myelodysplasia (HR-MDS), or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN). U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Sanofi