Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFC0ZB)

Drug Name

PF-07242813 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Atopic dermatitis	EA80	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

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Drug(s) Targeting T-cell surface glycoprotein CD1a (CD1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Antithymocyte globulin	DMH4CFE	Aplastic anemia	3A70	Approved	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
T-cell surface glycoprotein CD1a (CD1A)	TTBGTFN	CD1A_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT04668066) A PHASE 1 FIRST IN HUMAN, RANDOMIZED, DOUBLE BLIND, SPONSOR OPEN, PLACEBO-CONTROLLED, SINGLE- AND MULTIPLE DOSE ESCALATION, PARALLEL GROUP STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF PF 07242813 IN HEALTHY PARTICIPANTS AND PARTICIPANTS WITH ATOPIC DERMATITIS. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Pfizer
3	Acute sensory neuropathy associated with rabbit antithymocyte globulin. Am J Transplant. 2007 Feb;7(2):484-6.