Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFG7CC)

Drug Name

OTB-658 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Tuberculosis	1B10-1B14	Preclinical	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

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Drug(s) Targeting Bacterial Ribosome (Bact RIBS)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
TP-434	DM5A31S	Intra-abdominal infection	1A40	Approved	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Ribosome (Bact RIBS)	TTND3XS	NOUNIPROTAC	Inhibitor	[2]

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References

1	In Vitro and In Vivo Activity of Oxazolidinone Candidate OTB-658 against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0097421.
2	Clinical pipeline report, company report or official report of TB
3	Target- and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic. Antimicrob Agents Chemother. 2012 May;56(5):2559-64.