Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFP1C5)

Drug Name

indirubin derivative E804 Drug Info

Synonyms

indirubin E804; compound 2 [PMID: 21632247]

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Tyrosine-protein kinase EIF2AK2 (p68)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9650366, 12	DMR3Z49	N. A.	N. A.	Patented	[2]
US9650366, 2	DM9HZ03	N. A.	N. A.	Patented	[2]
US9650366, 9	DMUCIPE	N. A.	N. A.	Patented	[2]
NU6140	DMCUSG3	Discovery agent	N.A.	Investigative	[1]
ASN-11124542	DMFNZOI	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosine-protein kinase EIF2AK2 (p68)	TTXEZJ4	E2AK2_HUMAN	Inhibitor	[1]

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References

1	Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.
2	Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors. US9650366.
3	Small molecule inhibitors of the RNA-dependent protein kinase. Biochem Biophys Res Commun. 2003 Aug 15;308(1):50-7.