Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMG8KXR)

Drug Name

N-(Naphthalene-2-yl)ethyl-ETAV Drug Info

Synonyms

N-(Naphthalene-2-yl)ethyl-ETAV; CHEMBL493689

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Presynaptic density protein 95 (DLG4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tat-NR2B9c	DMD6AUX	Cerebrovascular ischaemia	8B1Z	Phase 3	[2]
2-Methyl-2,4-Pentanediol	DMD45CU	Discovery agent	N.A.	Investigative	[3]
Guanosine-5'-Monophosphate	DM3SLZK	Discovery agent	N.A.	Investigative	[3]
KSG-YEKLSSIESDV	DMPLFRC	Discovery agent	N.A.	Investigative	[1]
N-(3,4-Difluorophenyl)propyl-ETAV	DMF2D4O	Discovery agent	N.A.	Investigative	[1]
N-Propyl-ETAV	DMUTDNV	Discovery agent	N.A.	Investigative	[1]
N-Phenylethyl-ETAV	DM1VSO9	Discovery agent	N.A.	Investigative	[1]
N-Cyclohexylmethyl-ETAV	DMIC8Z6	Discovery agent	N.A.	Investigative	[1]
FETAV	DMO1N2T	Discovery agent	N.A.	Investigative	[1]
N-Butyl-ETAV	DMY3HEF	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Presynaptic density protein 95 (DLG4)	TT9PB26	DLG4_HUMAN	Inhibitor	[1]

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References

1	Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. J Med Chem. 2008 Oct 23;51(20):6450-9.
2	Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature. 2012 Feb 29;483(7388):213-7.
3	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.