Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGE8FK)

Drug Name

AMR-001 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Heart failure	BD10-BD13	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Preclinical Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Hematopoietic progenitor cell antigen CD34 (CD34)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CART-34 cells	DMRNIB9	Acute myeloid leukaemia	2A60	Phase 1	[3]
CAR-T cells targeting CD34	DM3G0OP	Acute myeloid leukaemia	2A60	Preclinical	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hematopoietic progenitor cell antigen CD34 (CD34)	TTZAVYN	CD34_HUMAN	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT01495364) NBS10 (Also Known as AMR-001) Versus Placebo Post ST Segment Elevation Myocardial Infarction. U.S. National Institutes of Health.
2	National Cancer Institute Drug Dictionary (drug id 743421).
3	ClinicalTrials.gov (NCT03291444) CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS
4	ClinicalTrials.gov (NCT03473457) CAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia