Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGS7CE)

Drug Name
8-(1,3,3-Trimethyl-butoxy)-quinolin-2-ylamine Drug Info
Synonyms CHEMBL183159; 8-(1,3,3-Trimethyl-butoxy)-quinolin-2-ylamine; SCHEMBL5884151; ZDVPLVAZUCNXKZ-UHFFFAOYSA-N; BDBM50152425
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10083869
TTD Drug ID
DMGS7CE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Melanin-concentrating hormone receptor 1 (MCHR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BMS-830216 DMCW71N Obesity 5B81 Phase 1 [2]
AZD1979 DMQ1OX4 Obesity 5B81 Phase 1 [3]
PMID25522065-Compound-27 DMXN4KB N. A. N. A. Patented [4]
PMID25522065-Compound-29 DMBNAK9 N. A. N. A. Patented [4]
PMID25522065-Compound-34 DMZDIRQ N. A. N. A. Patented [4]
PMID25522065-Compound-39 DM5YMQH N. A. N. A. Patented [4]
PMID25522065-Compound-40 DMCIQ01 N. A. N. A. Patented [4]
PMID25522065-Compound-11 DM410Z6 N. A. N. A. Patented [4]
PMID25522065-Compound-50 DMBWA0V N. A. N. A. Patented [4]
PMID25522065-Compound-12 DMVKO9C N. A. N. A. Patented [4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Melanin-concentrating hormone receptor 1 (MCHR1) TTX4RTB MCHR1_HUMAN Inhibitor [1]

References

1 Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 2. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4879-82.
2 2011 Pipeline of Bristol-Myers Squibb.
3 Phase I clinical trial of AZD1979 for treating obesity. AstraZeneca plc
4 Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207.