Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGXPJV)

Drug Name

3-(4,5-Bis-biphenyl-4-yl-1H-imidazol-2-yl)-phenol Drug Info

Synonyms

3-(4,5-Bis-biphenyl-4-yl-1H-imidazol-2-yl)-phenol; 296792-52-4; CHEMBL443007; 3-[4,5-bis(4-phenylphenyl)-1H-imidazol-2-yl]phenol; AC1M4HYZ; AC1Q790A; CTK8A0066; MolPort-001-732-645; ZINC6028400; BDBM50113297; STK758717; AKOS001063669; NE26785; MCULE-4347250395; UPCMLD0ENAT5224754:001; ST4040901; KB-335272; EN300-07381; 3-[4,5-bis(4-phenylphenyl)imidazol-2-yl]phenol; SR-01000521283; J-510645; SR-01000521283-1; Z56935326; 3-[4,5-di(biphenyl-4-yl)-1H-imidazol-2-yl]phenol; 3-(4,5-bis-biphenyl-4-yl-1h-imidazol-2-yl)phenol

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2259222
TTD Drug ID: DMGXPJV

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting PTPN1 messenger RNA (PTPN1 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[2]
TRYPAN BLUE	DM4NTMO	Ophthalmic surgery injury	PK97	Approved	[3]
URSOLIC ACID	DM4SOAW	Metabolic syndrome x	5C50-5D2Z	Phase 2	[4]
ISIS 113715	DMUPD4G	Type-2 diabetes	5A11	Phase 2	[5]
ISIS-PTP1Brx	DMJGVXT	Type-2 diabetes	5A11	Phase 2	[6]
ERTIPROTAFIB	DMJXEV7	Type-2 diabetes	5A11	Terminated	[7]
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[8]
B-Octylglucoside	DMMO75G	Discovery agent	N.A.	Investigative	[8]
2-Methyl-2,4-Pentanediol	DMD45CU	Discovery agent	N.A.	Investigative	[8]
Double Oxidized Cysteine	DM6TU84	Discovery agent	N.A.	Investigative	[8]
------------------------------------------------------------------------------------


⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
PTPN1 messenger RNA (PTPN1 mRNA)	TTELIN2	PTN1_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B. J Med Chem. 2002 May 23;45(11):2213-21.
2	Periodinates: a new class of protein tyrosine phosphatase inhibitors. Bioorg Med Chem Lett. 1999 Feb 8;9(3):353-6.
3	Evans Blue and other dyes as protein tyrosine phosphatase inhibitors. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1923-6.
4	Cytotoxic and PTP1B inhibitory activities from Erythrina abyssinica. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6745-9.
5	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2009).
6	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals.
7	2-O-carboxymethylpyrogallol derivatives as PTP1B inhibitors with antihyperglycemic activity. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5357-60.
8	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.