Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMH3TV7)

Drug Name

GNSC-001 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Osteoarthritis	FA00-FA05	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Interleukin-1 receptor antagonist protein (IL1RN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Humantakinogene hadenovec	DMOQOKZ	Osteoarthritis	FA00-FA05	Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin-1 receptor antagonist protein (IL1RN)	TT6GSR3	IL1RA_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT05835895) A Phase 1b, Randomized, Double-Blinded, Placebo-Controlled Dose Ranging Study to Evaluate Safety, Tolerability and Pharmacodynamics of a Single Intra-articular Injection of GNSC-001 Gene Therapy in Subjects With Osteoarthritis of the Knee. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Genascence
3	ClinicalTrials.gov (NCT04119687) An Open-Label, Single Ascending Dose Study to Assess the Safety and Tolerability of FX201 in Patients With Osteoarthritis of the Knee. U.S.National Institutes of Health.