Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMH9RTV)

Drug Name

Omigapil Drug Info

Synonyms

Omigapil); CGP-3466; CGP-3499B; Neuroprotectant, Novartis; Neuroprotectant, Santhera; Nootropic agent, Novartis; Nootropicagent, Santhera; SNT-317; TCH-346; TCH-346B

Indication

Disease Entry	ICD 11	Status	REF
Lateral sclerosis	8B61	Phase 2	[1]
Muscular dystrophy	8C70	Phase 1	[2]

Cross-matching ID

PubChem CID: 6419718
ChEBI ID: CHEBI:41778
CAS Number: CAS 181296-84-4
TTD Drug ID: DMH9RTV

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Saframycin A	DMZWGVP	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	TTUGSWA	G3P_HUMAN	Modulator	[3]

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References

1	ClinicalTrials.gov (NCT00649961) Melatonin As A Novel Neuroprotectant In Preterm Infants- Dosage Study. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Neuroprotection by pharmacologic blockade of the GAPDH death cascade. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3887-9.
4	Identification of GAPDH as a protein target of the saframycin antiproliferative agents. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5862-6.