General Information of Drug (ID: DMHBD1T)

Drug Name
5-(2-hydroxyethyl)nonane-1,9-diol Drug Info
Synonyms 5-(2-Hydroxyethyl)nonane-1,9-Diol; DB07171
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
25058136
TTD Drug ID
DMHBD1T

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
SCH-54470 DMEWLZ7 N. A. N. A. Terminated [2]
LY-292223 DML36ZE Discovery agent N.A. Investigative [3]
CGS 35066 DMCHT27 Discovery agent N.A. Investigative [4]
PO3 2-Nle-Trp-O-3K DMW1XY4 Discovery agent N.A. Investigative [5]
PMID19899765C22 DMBTV20 Discovery agent N.A. Investigative [2]
PO3 2-Leu-Trp-O-3K DM3O78D Discovery agent N.A. Investigative [5]
PO3 2-Ile-Trp-O-3K DMQMDSG Discovery agent N.A. Investigative [5]
PD159790 DM6RVTO Discovery agent N.A. Investigative [6]
PO3 2-Leu-Nal-O-3K DMY43FU Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 9 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Endothelin-converting enzyme 1 (ECE1) TTQ9RYT ECE1_HUMAN Inhibitor [1]

References

1 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2 Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors. J Med Chem. 2010 Jan 14;53(1):208-20.
3 Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells. J Med Chem. 2005 Jan 27;48(2):483-98.
4 The therapeutic potential of endothelin-1 receptor antagonists and endothelin-converting enzyme inhibitors on the cardiovascular system. Expert Opin Investig Drugs. 2002 Nov;11(11):1537-52.
5 Aminophosphonate endothelin converting enzyme inhibitors: potency-enhancing and selectivity-improving modifications of phosphoramidon, Bioorg. Med. Chem. Lett. 4(10):1257-1262 (1994).
6 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1615).