Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHI8RS)

Drug Name

HCBE-11 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Lymphotoxin beta receptor (LTBR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Baminercept	DMSZOXQ	Rheumatoid arthritis	FA20	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Lymphotoxin beta receptor (LTBR)	TTFO0PM	TNR3_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT00105170) Safety and Tolerability of hCBE-11 in Subjects With Advanced Solid Tumors. U.S. National Institutes of Health.
2	Lymphotoxin beta receptor activation on macrophages induces cross-tolerance to TLR4 and TLR9 ligands. J Immunol. 2012 Apr 1;188(7):3426-33.
3	ClinicalTrials.gov (NCT01552681) Baminercept in Sj ren's Syndrome. U.S. National Institutes of Health.