General Information of Drug (ID: DMHOJ0Z)

Drug Name
ISIS 298746 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DMHOJ0Z

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PT2385 DMCSN69 Recurrent glioblastoma 2A00.00 Phase 2 [2]
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol DM15P2G Discovery agent N.A. Investigative [3]
ISIS 298697 DM0WH1L Discovery agent N.A. Investigative [1]
ISIS 298744 DM8VMQ4 Discovery agent N.A. Investigative [1]
ISIS 298745 DM9YMPI Discovery agent N.A. Investigative [1]
ISIS 298743 DMD3NSQ Discovery agent N.A. Investigative [1]
ISIS 298702 DM4L7NE Discovery agent N.A. Investigative [1]
ISIS 298700 DM3DE98 Discovery agent N.A. Investigative [1]
ISIS 175510 DMPAXR4 Discovery agent N.A. Investigative [1]
ISIS 298699 DMB28JW Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HIF1-alpha messenger RNA (HIF1A mRNA) TTSN6QU HIF1A_HUMAN Not Available [1]

References

1 US patent application no. 7,217,572, Modulation of HIF1.alpha. and HIF2.alpha. expression.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6305-10.