Details of the Drug-Related molecule(s) Interaction Atlas

SCHEMBL15198146 Drug Info

SCHEMBL15198146

Cross-matching ID

PubChem CID

71715084

TTD Drug ID

DMHPQI2

General Information of Drug (ID: DMHPQI2)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Ubiquitin-activating enzyme E1 (UBAE1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SCHEMBL15198145	DMKQ0GE	N. A.	N. A.	Patented	[1]
QCPOIDRINIAUKU-SRBBEKPSSA-N	DM4DJA7	N. A.	N. A.	Patented	[1]
PYZD-4409	DME0NO8	leukaemia	2A60-2B33	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ubiquitin-activating enzyme E1 (UBAE1)	TTXHWA7	UBA1_HUMAN	Inhibitor	[1]

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References

1	Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme. US10202389.
2	The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma. Blood. 2010 Mar 18;115(11):2251-9.