Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHPV8A)

Drug Name

GALANIN Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Galanin receptor type 2 (GAL2-R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GwTLNSAGYLLGPHAVGNHRSFSDKNGLTS-CONH2	DMPIRE0	Discovery agent	N.A.	Investigative	[4]
[Sar1Gly]GAL-B2	DMUI0XV	Discovery agent	N.A.	Investigative	[4]
(Sar)WTLNSAGYLLGPKK(Lys-lauroyl)K	DMPZHIE	Discovery agent	N.A.	Investigative	[5]
GalB2	DMGX6UH	Discovery agent	N.A.	Investigative	[4]
(Sar)WTLNSAGYLLGPKK(Lys-octanoyl)K	DMX3K4E	Discovery agent	N.A.	Investigative	[5]
(Sar)WTLNSAGYLLGPKK(Lys-decanoyl)K	DMJL8SE	Discovery agent	N.A.	Investigative	[5]
(Sar)WTLNSAGYLLGPKK(Lys-MPEG4)K	DMQIHZU	Discovery agent	N.A.	Investigative	[5]
[Sar1Ala]GAL-B2	DMUD0LA	Discovery agent	N.A.	Investigative	[4]
GWTLNSAGYLLGPHAV-NH2	DMZPRIG	Discovery agent	N.A.	Investigative	[6]
GWTLNSAGYLLGPrPKPQQwFwLL-CONH2	DM48AV3	Discovery agent	N.A.	Investigative	[4]
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Drug(s) Targeting Galanin receptor type 1 (GAL1-R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GwTLNSAGYLLGPHAVGNHRSFSDKNGLTS-CONH2	DMPIRE0	Discovery agent	N.A.	Investigative	[4]
[Sar1Gly]GAL-B2	DMUI0XV	Discovery agent	N.A.	Investigative	[4]
(Sar)WTLNSAGYLLGPKK(Lys-lauroyl)K	DMPZHIE	Discovery agent	N.A.	Investigative	[5]
GalB2	DMGX6UH	Discovery agent	N.A.	Investigative	[4]
(Sar)WTLNSAGYLLGPKK(Lys-octanoyl)K	DMX3K4E	Discovery agent	N.A.	Investigative	[5]
(Sar)WTLNSAGYLLGPKK(Lys-decanoyl)K	DMJL8SE	Discovery agent	N.A.	Investigative	[5]
(Sar)WTLNSAGYLLGPKK(Lys-MPEG4)K	DMQIHZU	Discovery agent	N.A.	Investigative	[5]
[Sar1Ala]GAL-B2	DMUD0LA	Discovery agent	N.A.	Investigative	[4]
GWTLNSAGYLLGPHAV-NH2	DMZPRIG	Discovery agent	N.A.	Investigative	[6]
GWTLNSAGYLLGPrPKPQQwFwLL-CONH2	DM48AV3	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6129).
2	cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain... J Med Chem. 2008 Nov 27;51(22):7094-8.
3	Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. J Med Chem. 2008 Jul 24;51(14):4150-69.
4	Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic de... J Med Chem. 2010 Feb 25;53(4):1871-5.
5	Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues. J Med Chem. 2009 Mar 12;52(5):1310-6.
6	Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities. J Med Chem. 2008 Dec 25;51(24):8038-47.