General Information of Drug (ID: DMHXWZB)

Drug Name
Pyridine-carboximide derivative 2 Drug Info
Synonyms PMID25470667-Compound-Figure5-6
Cross-matching ID
PubChem CID
56837993
TTD Drug ID
DMHXWZB

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [2]
LCQ908 DMFLJHQ Familial chylomicronemia syndrome 5C80 Phase 3 [3]
AZD7687 DMS9I6A Diabetic complication 5A2Y Phase 1 [4]
P-7435 DMNZQU5 Diabetic complication 5A2Y Phase 1 [5]
PMID25470667-Compound-Figure4-1A DMMVQW8 N. A. N. A. Patented [1]
Azole derivative 7 DMVUJGI N. A. N. A. Patented [1]
Carbamide derivative 3 DM4ISCQ N. A. N. A. Patented [1]
T863 DMX41ZF Discovery agent N.A. Patented [1]
Benzamide derivative 19 DM5YNTM N. A. N. A. Patented [1]
Lactam derivative 5 DMX5FYZ N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Diacylglycerol acyltransferase 1 (DGAT1) TTF8P9I DGAT1_HUMAN Inhibitor [1]

References

1 Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58.
2 In vitro inhibition of diacylglycerol acyltransferase by prenylflavonoids from Sophora flavescens. Planta Med. 2004 Mar;70(3):258-60.
3 DGAT1 inhibitors as anti-obesity and anti-diabetic agents. Curr Opin Drug Discov Devel. 2010 Jul;13(4):489-96.
4 Clinical pipeline report, company report or official report of AstraZeneca (2011).
5 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033014)