General Information of Drug (ID: DMI4O92)

Drug Name
LFA-102 Drug Info
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMI4O92

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Prolactin receptor (PRLR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Endostatin DM8NLDI Solid tumour/cancer 2A00-2F9Z Phase 2 [3]
Prolanta DMLKF3H Fallopian tube cancer 2C74 Phase 1 [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prolactin receptor (PRLR) TTBPXMA PRLR_HUMAN Not Available [2]

References

1 ClinicalTrials.gov (NCT01610050) A Phase I Study of LFA102 in Japanese Patients. U.S. National Institutes of Health.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1721).
3 Prolactin antagonist-endostatin fusion protein as a targeted dual-functional therapeutic agent for breast cancer. Cancer Res. 2003 Jul 1;63(13):3598-604.
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)