Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMI5TXZ)

Drug Name

AEM-28 Drug Info

Synonyms

Apo-E peptide mimetic (acute coronary syndrome), University of Alabama at Birmingham/LipimetiX

Indication

Disease Entry	ICD 11	Status	REF
Familial hypercholesterolemia	5C80.00	Phase 2	[1]
Hyperlipidaemia	5C80	Phase 1/2	[2]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Apolipoprotein E (APOE)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CN-105	DM0MTP8	Nontraumatic intracerebral hemorrhage	8B00.4	Phase 2	[4]
LX1001	DMXEJZO	Alzheimer disease	8A20	Phase 1/2	[5]
Apolipoprotein E	DMIYTPE	Glaucoma/ocular hypertension	9C61	Terminated	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	ClinicalTrials.gov (NCT02100839) Safety Study of AEM-28 to Treat Refractory Hypercholesterolemia. U.S. National Institutes of Health.
3	Clinical pipeline report, company report or official report of LipimetiX.
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5	Clinical pipeline report, company report or official report of Lexeo Therapeutics
6	Apolipoprotein E: a potent inhibitor of endothelial and tumor cell proliferation. J Cell Biochem. 1994 Mar;54(3):299-308.