Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMI7A6R)

• Drug Name: Narciclasine Drug Info
• Synonyms: Narciclasine; Lycoricidinol; 29477-83-6; Lycoricidin-A; Narciclasina; NSC 266535; BRN 1087400; NSC266535; Lycorcidinol; Nacriclasine; C14H13NO7; CHEMBL98745; 3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one; CHEBI:70169; (2s,3r,4s,4ar)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(2h)-one; (2S,3R,4S,4aR)-2,3,4,7-Tetrahydroxy-3,4,4a,5-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one

Indication

Disease Entry	ICD 11	Status	REF
Melanoma	2C30	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 72376
  ChEBI ID: CHEBI:70169
  CAS Number: CAS 29477-83-6
  TTD Drug ID: DMI7A6R

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Elongation factor 1A (EF1A)	TT8R0BZ	EF1A1_HUMAN; EF1A2_HUMAN	Inhibitor	[1]

References

• [1] Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas. FASEB J. 2010 Nov;24(11):4575-84.