Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMINXMY)

Drug Name	CID 138805970 Drug Info
Cross-matching ID	PubChem CID 138805970 TTD Drug ID DMINXMY

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Preclinical Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Ribosomal protein S6 kinase alpha-6 (RSK6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US10081632, Compound 25	DM3BDHN	N. A.	N. A.	Patented	[1]
BI-D1870	DMK3SAF	Chronic lymphocytic leukaemia	2A82.0	Preclinical	[2]
PMID22564207C25b	DMBMYKQ	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ribosomal protein S6 kinase alpha-6 (RSK6)	TT3KYWB	KS6A6_HUMAN	Inhibitor	[1]

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References

1	Substituted tetrahydropyrido[3,2:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors. US9771366.
2	BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem J. 2007 Jan 1;401(1):29-38.
3	Discovery of an orally efficacious inhibitor of anaplastic lymphoma kinase. J Med Chem. 2012 May 24;55(10):4580-93.