Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIQ31Y)

Drug Name

Custirsen Drug Info

Synonyms

OGX-001/TV-1011; OGX-011

Indication

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Phase 3	[1]
Lung cancer	2C25.0	Phase 3	[1]
Prostate cancer	2C82.0	Phase 3	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Clusterin messenger RNA (Clusterin mRNA)	TTRL76H	CLUS_HUMAN	Not Available	[2]

------------------------------------------------------------------------------------

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016680)
2	Over-expression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors. Eur J Cancer. 2009 Jul;45(10):1846-54.