Details of the Drug-Related molecule(s) Interaction Atlas

US8791257, 4 Drug Info

SCHEMBL14634987; SCHEMBL12284249; CHEMBL3681193; DZUXIHIXWCKJDW-HAQNSBGRSA-N; BDBM127318; US8791257, 4; 4-Amino-N-(trans-4-hydroxycyclohexyl)-7-(2-fluoro-4-pyridinyl)pyrrolo[2,1-f][1,2,4]triazine-5-carboxamide

Cross-matching ID

PubChem CID

68230695

TTD Drug ID

DMIQO8N

General Information of Drug (ID: DMIQO8N)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Casein kinase II alpha prime (CSNK2A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US8940736, 6	DMXY4SP	N. A.	N. A.	Patented	[2]
US8940736, 23	DM3PU57	N. A.	N. A.	Patented	[2]
US8791257, 38	DMAEHCP	N. A.	N. A.	Patented	[1]
US8791257, 17	DMUPRX2	N. A.	N. A.	Patented	[1]
US8940736, 7	DM9KSVI	N. A.	N. A.	Patented	[2]
PMID22115617C2c	DMX5UKA	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Casein kinase II alpha prime (CSNK2A2)	TTR93NU	CSK22_HUMAN	Inhibitor	[1]

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References

1	Substituted pyrrolotriazines as protein kinase inhibitors. US8791257.
2	Imidazotriazinecarbonitriles useful as kinase inhibitors. US8940736.
3	CK2alpha and CK2alpha' subunits differ in their sensitivity to 4,5,6,7-tetrabromo- and 4,5,6,7-tetraiodo-1H-benzimidazole derivatives. Eur J Med Chem. 2012 Jan;47(1):345-50.