Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMITYCN)

Drug Name
PF-3557156 Drug Info
Synonyms PDE 7 inhibitor (pain), Pfizer; Phosphodiesterase 7 inhibitor (pain), Pfizer
Indication
Disease Entry ICD 11 Status REF
Pain MG30-MG3Z Discontinued in Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMITYCN

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Phosphodiesterase 7B (PDE7B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
SCH51866 DMCWSJP Discovery agent N.A. Investigative [3]
BRL50481 DMV2XUM Discovery agent N.A. Investigative [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 7A (PDE7A) TT1BC3A PDE7A_HUMAN Modulator [2]
Phosphodiesterase 7B (PDE7B) TTWIEY9 PDE7B_HUMAN Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026842)
2 Company report (Pfizer pipeline: October 28, 2008)
3 Identification of human PDE7B, a cAMP-specific phosphodiesterase. Biochem Biophys Res Commun. 2000 May 19;271(3):575-83.
4 New classes of PDE7 inhibitors identified by a fission yeast-based HTS. J Biomol Screen. 2010 Apr;15(4):359-67.