Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIWMZY)

Drug Name

LP-403812 Drug Info

Synonyms

LP 403812; LP403812

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Sodium-dependent proline transporter (SLC6A7)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID25037917C58	DMJPR8M	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sodium-dependent proline transporter (SLC6A7)	TT9LGO5	SC6A7_HUMAN	Inhibitor	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4576).
2	Discovery and characterization of potent small molecule inhibitors of the high affinity proline transporter. Neurosci Lett. 2009 Feb 27;451(3):212-6.
3	Novel inhibitors of the high-affinity L-proline transporter as potential therapeutic agents for the treatment of cognitive disorders. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3886-90.