General Information of Drug (ID: DMIYTPE)

Drug Name
Apolipoprotein E Drug Info
Synonyms Apolipoprotein E, Bio-Technology General; Apo-A4, Bio-Technology General; Apo-E, Bio-Technology General; Apolipoprotein-A4, Bio-Technology General
Indication
Disease Entry ICD 11 Status REF
Glaucoma/ocular hypertension 9C61 Terminated [1]
Cross-matching ID
TTD Drug ID
DMIYTPE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Apolipoprotein E (APOE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
AEM-28 DMI5TXZ Familial hypercholesterolemia 5C80.00 Phase 2 [3]
CN-105 DM0MTP8 Nontraumatic intracerebral hemorrhage 8B00.4 Phase 2 [4]
LX1001 DMXEJZO Alzheimer disease 8A20 Phase 1/2 [5]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Apolipoprotein E (APOE) TTKS9CB APOE_HUMAN Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000261)
2 Apolipoprotein E: a potent inhibitor of endothelial and tumor cell proliferation. J Cell Biochem. 1994 Mar;54(3):299-308.
3 Clinical pipeline report, company report or official report of LipimetiX.
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 Clinical pipeline report, company report or official report of Lexeo Therapeutics