Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJBTZG)

• Drug Name: Pyrrolo[2,3-b]pyridine derivative 4 Drug Info
• Synonyms: PMID25656651-Compound-24
• Cross-matching ID:
  PubChem CID: 89899422
  TTD Drug ID: DMJBTZG

Molecule-Related Drug Atlas

Drug(s) Targeting Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID25656651-Compound-37b	DMX98YV	N. A.	N. A.	Patented	[1]
PMID25656651-Compound-36a	DMNXVY9	N. A.	N. A.	Patented	[1]
PMID25656651-Compound-37c	DM684IK	N. A.	N. A.	Patented	[1]
PMID25656651-Compound-36d	DMKMY4I	N. A.	N. A.	Patented	[1]
PMID25656651-Compound-36b	DMHYDM7	N. A.	N. A.	Patented	[1]
PMID25656651-Compound-36c	DMOGKSW	N. A.	N. A.	Patented	[1]
PMID25656651-Compound-19b	DMI1Z7D	N. A.	N. A.	Patented	[1]
PMID25656651-Compound-37a	DM0P4F3	N. A.	N. A.	Patented	[1]
PMID25656651-Compound-19a	DMSNUVZ	N. A.	N. A.	Patented	[1]
Indazole derivative 5	DMM1I8R	N. A.	N. A.	Patented	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I)	TTIV39N	BCR_HUMAN-ABL1_HUMAN	Inhibitor	[1]

References

• [1] Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412.