Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJGFLD)

Drug Name

PMID15026062C41 Drug Info

Synonyms

GTPL6702; BDBM50142719

Indication

Disease Entry	ICD 11	Status	REF
Pancreatitis	DC31-DC34	Clinical trial	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Hormone sensitive lipase (LIPE)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BENZYL BENZOATE	DMDPYI5	Infestations of lice and scabies	1G00.Z	Approved	[2]
OXYBENZONE	DMMZYX6	Discovery agent	N.A.	Investigative	[3]
ETHIOFENCARB	DMQTEDP	Discovery agent	N.A.	Investigative	[3]
NCI-58425	DM9C7GP	Discovery agent	N.A.	Investigative	[3]
2-(3-methoxybenzylthio)-2-phenylacetic acid	DM21MAU	Discovery agent	N.A.	Investigative	[3]
BIFENOX	DM4MUXT	Discovery agent	N.A.	Investigative	[3]
NCI-159878	DMTCBLS	Discovery agent	N.A.	Investigative	[3]
PMI-008	DMHX704	Obesity	5B81	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hormone sensitive lipase (LIPE)	TTLUQ8E	LIPS_HUMAN	Inhibitor	[1]

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References

1	Carbazates as potent inhibitors of hormone-sensitive lipase. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1741-4.
2	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
3	Combining ligand-based pharmacophore modeling, quantitative structure-activity relationship analysis and in silico screening for the discovery of n... J Med Chem. 2008 Oct 23;51(20):6478-94.
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2593).