Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJK7V0)

Drug Name

Ge2270a Drug Info

Synonyms

GE 2770; GE-2270; 134861-34-0; SCHEMBL12519961; CHEBI:29584; LS-187584; LS-186934

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Plasmodium Elongation factor 1-alpha 1 (Malaria MEF-1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Guanosine-5'-Diphosphate	DM0MUKQ	Discovery agent	N.A.	Investigative	[2]
Amythiamicin	DM7SHQ1	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasmodium Elongation factor 1-alpha 1 (Malaria MEF-1)	TTG45NU	EF1A_PLAFK	Inhibitor	[2]

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References

1	In vitro antimicrobial activity of a new antibiotic, MDL 62,879 (GE2270 A).. Antimicrob Agents Chemother. 1993 April; 37(4): 741-745.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3	The apicoplast as an antimalarial drug target. Drug Resist Updat. 2001 Jun;4(3):145-51.