Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJKW4S)

• Drug Name: Isocitric Acid Drug Info
• Synonyms: Citric acid, tetrakis(trimethylsilyl) deriv.; 1,2,3-Propanetricarboxylic acid, 2-[(trimethylsilyl)oxy]-, tris(trimethylsilyl) ester; Citric acid, (4TMS); Citric acid, tetra-TMS; Citric acid, tetrakis-TMS; CITRIC ACID-TETRA-TMS; Citric acid, 4TMS derivative; AC1LB862; CTK7F4886; VFGAVMGYDWDESE-UHFFFAOYSA-N; 14330-97-3; 3-O-Trimethylsilylcitric acid tri(trimethylsilyl) ester; Citric acid, trimethylsilyl ether, tris(trimethylsilyl) ester; tris(trimethylsilyl) 2-trimethylsilyloxypropane-1,2,3-tricarboxylate

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 1198
  ChEBI ID: CHEBI:30887
  CAS Number: CAS 320-77-4
  TTD Drug ID: DMJKW4S

Molecule-Related Drug Atlas

Drug(s) Targeting Citrate hydro-lyase (ACO2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aconitate Ion	DMJ5U8C	Discovery agent	N.A.	Investigative	[1]
Alpha-Methylisocitric Acid	DM3YGWL	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-Aconitate Ion	DMT8L5R	Discovery agent	N.A.	Investigative	[1]
Tricarballylic Acid	DMLKWTG	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Citrate hydro-lyase (ACO2)	TTMTF2P	ACON_HUMAN	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.