Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJVNQB)

Drug Name

(-)-hydroxycitrate Drug Info

Synonyms

Garcinia acid; 3-c-carboxy-2-deoxy-d-erythro-pentaric acid; CHEMBL118715; UNII-8W94T9026R; (1S,2S)-1,2-dihydroxypropane-1,2,3-tricarboxylic acid; 8W94T9026R; Super CitriMax HCA 600SXS; 4373-35-7; (-)-Hydroxycitrate; 27750-10-3; 7A3; Citric acid, 2-hydroxy-, (-)-; AC1Q5QYE; AC1L4H7S; (2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid; SCHEMBL6773065; DTXSID20276669; ZINC1656422; BDBM50036210; LMFA01050511; AJ-28889; D-erythro-Pentaric acid,

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 185620
ChEBI ID: CHEBI:165420
CAS Number: CAS 27750-10-3
TTD Drug ID: DMJVNQB

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting ATP-citrate synthase (ACLY)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Bempedoic acid	DM1CI9R	Familial hypercholesterolemia	5C80.00	Approved	[2]
SB-201076	DMKLWSG	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
ATP-citrate synthase (ACLY)	TT0Z6Y2	ACLY_HUMAN	Inhibitor	[1]

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References

1	2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3208-11.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020
3	The biology and chemistry of hyperlipidemia. Bioorg Med Chem. 2007 Jul 15;15(14):4674-99.