Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJW8NV)

Drug Name

SQ-14603 Drug Info

Synonyms

2-Benzyl-3-mercaptopropanoic acid; SQ-14603; CHEMBL58957; 2-benzyl-3-sulfanylpropanoic acid; 69734-01-6; SQ 14,603; Benzenepropanoic acid, alpha-(mercaptomethyl)-; AC1Q5S0H; AC1L4Y1D; SCHEMBL1559014; CTK2F3831; ZUEBVBPVXLQMQR-UHFFFAOYSA-N; 2-Benzyl-3-mercapto-propionic acid; BDBM50109593; AKOS022645473; 2-mercaptomethyl-3-phenylpropionic acid; 2-Mercaptomethyl-3-phenyl-propionic acid; 81110-55-6; 3-Phenyl-2-(mercaptomethyl)propionic acid; Benzenepropanoic acid, alpha-(mercaptomethyl)-, (+-)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 194327
CAS Number: CAS 69734-01-6
TTD Drug ID: DMJW8NV

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Carboxypeptidase A1 (CPA1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DL-benzylsuccinic acid	DMHI9ZJ	Discovery agent	N.A.	Investigative	[2]
PMID18078750C1b	DMO21H5	Discovery agent	N.A.	Investigative	[3]
2-Thiomethyl-3-Phenylpropanoic Acid	DMCEK6N	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carboxypeptidase A1 (CPA1)	TT3LJ6G	CBPA1_HUMAN	Inhibitor	[1]

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References

1	Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. J Med Chem. 2007 Nov 29;50(24):6095-103.
2	A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases. Eur J Med Chem. 2009 Aug;44(8):3266-71.
3	Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite. Bioorg Med Chem Lett. 2008 Jan 15;18(2):732-7.
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1587).