Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMK6FYR)

• Drug Name: DiabeCell Drug Info
• Synonyms: Porcine pancreatic islet cell therapy (Immupel encapsulated, type 1 diabetes), LCT; Porcine pancreatic islet celltherapy (alginate encapsulated, type 1 diabetes), LCT

Indication

Disease Entry	ICD 11	Status	REF
Insulin-dependent diabetes	5A10	Phase 2	[1]

• Cross-matching ID: TTD Drug ID: DMK6FYR

Molecule-Related Drug Atlas

Drug(s) Targeting T-cells (T-cells)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ATG-Fresenius S	DM4VJ5Q	Transplant rejection	NE84	Phase 3	[3]
TVI-Kidney-1	DMGYSZ0	Renal cell carcinoma	2C90	Phase 2	[4]
Baltaleucel-T	DM3WCL4	Diffuse large B-cell lymphoma	2A81	Phase 2	[5]
T2c-001	DM06GDC	Congestive heart failure	BD10	Phase 2	[2]
BPX-501	DMIMA4V	Acute lymphoblastic leukaemia	2A85	Phase 1/2	[5]
AX-024	DMRQ32K	Multiple sclerosis	8A40	Phase 1	[6]
RTL-1000	DM1B4CQ	Multiple sclerosis	8A40	Phase 1	[7]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
T-cells (T-cells)	TTXQYT6	NOUNIPROTAC	Modulator	[2]

References

• [1] ClinicalTrials.gov (NCT01736228) Open-label Investigation of the Safety and Efficacy of DIABECELL in Patients With Type 1 Diabetes Mellitus. U.S. National Institutes of Health.
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [3] Clinical pipeline report, company report or official report of Neovii Biotech.
• [4] Clinical pipeline report, company report or official report of TVAX Biomedical.
• [5] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [6] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [7] RTL THERAPY FOR MULTIPLE SCLEROSIS: A Phase I Clinical Study. J Neuroimmunol. 2011 February; 231(1-2): 7-14.