Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMK9BP2)

Drug Name
Mavacamten Drug Info
Synonyms SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461
Indication
Disease Entry ICD 11 Status REF
Obstructive hypertrophic cardiomyopathy BC43.12 Approved [1]
Cross-matching ID
PubChem CID
117761397
CAS Number
CAS 1642288-47-8
TTD Drug ID
DMK9BP2

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Myosin (MYO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
MYK-491 DM9BREJ Dilated cardiomyopathy BC43.0 Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Myosin (MYO) TTITSMB NOUNIPROTAC Inhibitor [2]

References

1 FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 214998.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Effects of danicamtiv, a novel cardiac myosin activator, in heart failure with reduced ejection fraction: experimental data and clinical results from a phase 2a trial. Eur J Heart Fail. 2020 Sep;22(9):1649-1658.