General Information of Drug (ID: DMKHXT9)

Drug Name
9-[2-(1-Phosphonobutan-2-yloxy)ethyl]hypoxanthine Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
135867626
TTD Drug ID
DMKHXT9

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US9200020, Table 3, Compound 1B DMEARS2 N. A. N. A. Patented [2]
US9200020, Table 3, Compound 2B DMXFB5Z N. A. N. A. Patented [2]
US9200020, Table 3 compound 8 DMCLHX5 N. A. N. A. Patented [2]
Acetate Ion DMD08RH Discovery agent N.A. Investigative [3]
Formic Acid DMNFZC6 Discovery agent N.A. Investigative [3]
Pyrophosphate 2- DMZQ75M Discovery agent N.A. Investigative [4]
Guanosine-5'-Monophosphate DM3SLZK Discovery agent N.A. Investigative [3]
Inosinic Acid DMLR86H Discovery agent N.A. Investigative [3]
Alpha-Phosphoribosylpyrophosphoric Acid DMT6KI7 Discovery agent N.A. Investigative [4]
Carboxylic PRPP DMCTUR1 Discovery agent N.A. Investigative [3]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Plasmodium Hypoxanthine-guanine phosphoribosyltransferase (Malaria LACZ) TTBL49X HGXR_PLAFG Inhibitor [1]

References

1 Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum h... Bioorg Med Chem. 2009 Sep 1;17(17):6218-32.
2 6-oxopurine phosphoribosyltransferase inhibitors. US9200020.
3 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.