Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMKL7PL)

Drug Name

PF-07328948 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Heart failure with preserved ejection fraction	BD11.0	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
[3-methyl-2-oxobutanoate dehydrogenase] kinase (BCKDK)	TT7WD2Q	BCKD_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT05654181) A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED, 4-PERIOD, CROSSOVER, FIRST-IN-HUMAN STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE ASCENDING ORAL DOSES OF PF-07328948 ADMINISTERED TO HEALTHY ADULT PARTICIPANTS. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Pfizer