General Information of Drug (ID: DMKVONZ)

Drug Name
PMID20690647C4b Drug Info
Synonyms Cbz-Leu-D,L-Abu-CONH-(CH(2))(3)-2-methoxyadenin-9-yl; GTPL8614; BDBM50326300
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
25195974
TTD Drug ID
DMKVONZ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Drug(s) Targeting Calpain-2 (CAPN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ABT-957 DMB9N4J Alzheimer disease 8A20 Phase 1 [2]
PMID25399719-Compound-17 DMRXKJZ N. A. N. A. Patented [3]
Epoxysuccinate derivative 9 DM49FU0 N. A. N. A. Patented [3]
Epoxysuccinate derivative 4 DMCF6M8 N. A. N. A. Patented [3]
Carboxamide derivative 7 DM8TQS4 N. A. N. A. Patented [3]
Epoxysuccinate derivative 7 DMTSPVF N. A. N. A. Patented [3]
Carboxamide derivative 10 DM5WMO9 N. A. N. A. Patented [3]
Carboxamide derivative 11 DM1DN94 N. A. N. A. Patented [3]
Carboxamide derivative 8 DM6HI34 N. A. N. A. Patented [3]
Epoxysuccinate derivative 10 DMYF39U N. A. N. A. Patented [3]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calpain-2 (CAPN2) TTG5QB7 CAN2_HUMAN Inhibitor [1]

References

1 Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors. J Med Chem. 2010 Sep 9;53(17):6326-36.
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3 An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.