Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DML3K9N)

Drug Name

XTL-6865 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis C virus infection	1E51.1	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

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Drug(s) Targeting Hepatitis C virus Envelope glycoprotein E2 (HCV NS1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MBL-HCV1	DMJVU7Y	Hepatitis C virus infection	1E51.1	Phase 2	[3]
HuMax-HepC	DMFVB7Z	Hepatitis C virus infection	1E51.1	Terminated	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hepatitis C virus Envelope glycoprotein E2 (HCV NS1)	TTDBG95	POLG_HCV1	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT00300807) Study of XTL6865 in Patients With Chronic Hepatitis C Virus Infection. U.S. National Institutes of Health.
2	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3	Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: a randomized controlled study. Am J Transplant. 2013 Apr;13(4):1047-54.
4	Clinical pipeline report, company report or official report of Genmab.