Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DML5URN)

• Drug Name: (+/-)-2-Aminoindane-2-carboxylic acid Drug Info
• Synonyms: 27473-62-7; 2-Amino-2-indancarboxylic acid; 2-amino-2,3-dihydro-1H-indene-2-carboxylic acid; 2-Aminoindane-2-carboxylic acid; 2-AMINOINDAN-2-CARBOXYLIC ACID; 2-Aminoindan-2-carboxylicacid; 2-Amino-indan-2-carboxylic acid; 2-amino-1,3-dihydroindene-2-carboxylic acid; CHEMBL1082953; 2-azanyl-1,3-dihydroindene-2-carboxylic acid; 1H-Indene-2-carboxylicacid, 2-amino-2,3-dihydro-; 2-amino-2-indancarboxylicacid; NSC70943; (+/-)-2-Aminoindane-2-carboxylic acid; AC1L5IQE; AC1Q50FV; AC1Q5UK7; SCHEMBL122942; 1H-Indene-2-carboxylic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 250936
  CAS Number: CAS 27473-62-7
  TTD Drug ID: DML5URN

Molecule-Related Drug Atlas

Drug(s) Targeting Large neutral amino acids transporter 1 (SLC7A5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(+/-)-2-Amino-1,2,3,4-tetrahydro-2-naphthoic acid	DMX768L	Discovery agent	N.A.	Investigative	[1]
BCH	DM9IN0U	Discovery agent	N.A.	Investigative	[2]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Large neutral amino acids transporter 1 (SLC7A5)	TTPH2JB	LAT1_HUMAN	Inhibitor	[1]

References

• [1] Regiospecific and conformationally restrained analogs of melphalan and DL-2-NAM-7 and their affinities for the large neutral amino acid transporter... Bioorg Med Chem Lett. 2010 Jun 15;20(12):3688-91.
• [2] Amino acid transporter molecule as a drug target. Nippon Yakurigaku Zasshi. 1999 Oct;114 Suppl 1:11P-16P.