Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DML7Z1H)

Drug Name

ACVR2B Drug Info

Synonyms

ACVR2B program (muscle atrophy); ACVR2B program (muscle atrophy), Rigel Pharmaceuticals; Activin type IIB receptorantagonist, (small molecule therapeutic, muscle atrophy), Rigel Pharmaceuticals

Indication

Disease Entry	ICD 11	Status	REF
Muscle wasting disease	8E4A.3	Investigative	[1]

Cross-matching ID

TTD Drug ID: DML7Z1H

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Activin receptor type IIB (ACVR2B)	TTLFRKS	AVR2B_HUMAN	Antagonist	[1]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1792).