Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMLTU3J)

Drug Name
2-(2-butoxypyrimidin-4-ylamino)benzoic acid Drug Info
Synonyms 2-[(2-butoxypyrimidin-4-yl)amino]benzoic Acid; 4-anilinopyrimidine 1; AC1LZD2G; CHEMBL242488; BDBM15977; MolPort-002-549-430; ZINC2272106; STL297947; AKOS003630983; MCULE-6330252818
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1897784
TTD Drug ID
DMLTU3J

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Stress-activated protein kinase JNK1 (JNK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
NKP-1339 DM5AWK1 Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
PMID25991433-Compound-A1 DM89LF0 N. A. N. A. Patented [3]
PMID25991433-Compound-F2 DM37VIQ N. A. N. A. Patented [3]
7-azaindole derivative 1 DMQL5B7 N. A. N. A. Patented [3]
7-azaindole derivative 5 DMV3H98 N. A. N. A. Patented [3]
PMID25991433-Compound-P6 DMNDVC9 N. A. N. A. Patented [3]
PMID25991433-Compound-J3 DM17P3F N. A. N. A. Patented [3]
PMID25991433-Compound-P1 DMD8AX6 N. A. N. A. Patented [3]
PMID25991433-Compound-O3 DMVOWS5 N. A. N. A. Patented [3]
PMID25991433-Compound-L1 DM2135Y N. A. N. A. Patented [3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Stress-activated protein kinase JNK1 (JNK1) TT0K6EO MK08_HUMAN Inhibitor [1]

References

1 Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17(3):668-72.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1496).
3 c-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).Expert Opin Ther Pat. 2015;25(8):849-72.