Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMM1I8R)

Drug Name
Indazole derivative 5 Drug Info
Synonyms PMID25656651-Compound-35
Cross-matching ID
PubChem CID
6450551
ChEBI ID
CHEBI:66910
CAS Number
CAS 319460-85-0
TTD Drug ID
DMM1I8R
ACDINA Drug ID
D00053

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting ABL T315I mutant (ABL T315I)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID25656651-Compound-42 DMTUA6E N. A. N. A. Patented [1]
Drug(s) Targeting Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID25656651-Compound-37b DMX98YV N. A. N. A. Patented [1]
PMID25656651-Compound-36a DMNXVY9 N. A. N. A. Patented [1]
PMID25656651-Compound-37c DM684IK N. A. N. A. Patented [1]
PMID25656651-Compound-36d DMKMY4I N. A. N. A. Patented [1]
PMID25656651-Compound-36b DMHYDM7 N. A. N. A. Patented [1]
PMID25656651-Compound-36c DMOGKSW N. A. N. A. Patented [1]
PMID25656651-Compound-19b DMI1Z7D N. A. N. A. Patented [1]
PMID25656651-Compound-37a DM0P4F3 N. A. N. A. Patented [1]
PMID25656651-Compound-19a DMSNUVZ N. A. N. A. Patented [1]
Pyrrolo[2,3-b]pyridine derivative 4 DMJBTZG N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ABL T315I mutant (ABL T315I) TTZJTWA ABL1_HUMAN Inhibitor [1]
Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I) TTIV39N BCR_HUMAN-ABL1_HUMAN Inhibitor [1]

References

1 Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412.