Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMM8IAQ)

Drug Name

PNU-142731A Drug Info

Synonyms

9-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]-2,4-bis(pyrrolidin-1-yl)-9H-pyrimido[4,5-b]indole hydrochloride

Indication

Disease Entry	ICD 11	Status	REF
Asthma	CA23	Phase 2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Eosinophil/lymphocyte-rich accumulation (ELR accum)	TT26HJ8	NOUNIPROTAC	Modulator	[2]

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References

1	Clinical pipeline report, company report or official report of pubfacts.
2	Preclinical evaluation of anti-inflammatory activities of the novel pyrrolopyrimidine PNU-142731A, a potential treatment for asthma. J Pharmacol Exp Ther. 1999 Jul;290(1):188-95.