Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMOA2X)

Drug Name

Nikkomycin Z Drug Info

Synonyms

SP-920704

Indication

Disease Entry	ICD 11	Status	REF
Candidiasis	1F23	Phase 1/2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Candida Chitin synthase 3 (Candi CHS3)	TTBGVF1	CHS3_CANAX	Modulator	[2]

------------------------------------------------------------------------------------

References

1	ClinicalTrials.gov (NCT00614666) Safety and PK of Nikkomycin Z for Coccidioides Pneumonia Treatment. U.S. National Institutes of Health.
2	Inhibitory effect of nikkomycin Z on chitin synthases in Candida albicans. Yeast. 2002 Mar 15;19(4):341-9.