Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMOWT9)

Drug Name

GSK3640254 Drug Info

Synonyms

GSK'254

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus infection	1C62	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Human immunodeficiency virus Maturation (HIV Mat)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GSK2838232	DMCIGRW	Human immunodeficiency virus-1 infection	1C62	Phase 2	[3]
BMS-955176	DMMEAGO	Human immunodeficiency virus-1 infection	1C62	Phase 2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Human immunodeficiency virus Maturation (HIV Mat)	TT5TOX7	NOUNIPROTAC	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT03784079) A Proof of Concept Study of GSK3640254 in Human Immunodeficiency Virus-1 (HIV-1) Infected Treatment-naive Adults. U.S. National Institutes of Health.
2	Phase I evaluation of the safety, tolerability, and pharmacokinetics of GSK3640254, a next-generation HIV-1 maturation inhibitor. Pharmacol Res Perspect. 2020 Dec;8(6):e00671.
3	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037762)
4	Clinical pipeline report, company report or official report of Bristol-Myers Squibb.