Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMQZ3I)

Drug Name

HMR59 Drug Info

Synonyms

AAVCAGsCD59

Indication

Disease Entry	ICD 11	Status	REF
Dry age-related macular degeneration	9B75	Phase 2	[1]
Geographic retinal atrophy	9B78.9	Phase 2	[1]
Wet age-related macular degeneration	9B78.3Z	Phase 2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Membrane inhibitor of reactive lysis (CD59)	TTBGTEJ	CD59_HUMAN	Replacement	[2]

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References

1	ClinicalTrials.gov (NCT04358471) Intravitreal AAVCAGsCD59 for Advanced Dry Age-related Macular Degeneration (AMD) With Geographic Atrophy (GA). U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Hemera Biosciences.