Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMSA9Y)

Drug Name

DNL593 Drug Info

Synonyms

TAK-594

Indication

Disease Entry	ICD 11	Status	REF
Frontotemporal dementia	6D83	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Progranulin (PGRN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PBFT02	DMMXU5U	Frontotemporal dementia	6D83	Phase 1/2	[3]
PR-006	DMM7HKG	Frontotemporal dementia	6D83	Phase 1/2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT05262023) A Phase 1/2, Multicenter, Randomized, Placebo-Controlled, Double Blind Single Dose and Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia Followed by an Open-Label Extension. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Denali
3	Clinical pipeline report, company report or official report of Passage Bio
4	Clinical pipeline report, company report or official report of Prevail Therapeutics