Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMSBW5)

Drug Name

LY-545694 Drug Info

Synonyms

Lead iGluR5 antagonist (pain), Eli Lilly

Indication

Disease Entry	ICD 11	Status	REF
Neuropathic pain	8E43.0	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

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Drug(s) Targeting Glutamate receptor ionotropic (GRI)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NPS-846	DMNL1VM	Cerebrovascular ischaemia	8B1Z	Terminated	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glutamate receptor ionotropic (GRI)	TTDXZ24	NOUNIPROTAC	Antagonist	[2]

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References

1	ClinicalTrials.gov (NCT00785577) A Study for Treatment of Pain in Patients With Diabetic Neuropathy.. U.S. National Institutes of Health.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019739)
3	Neuroprotective effects of NPS 846, a novel N-methyl-D-aspartate receptor antagonist, after closed head trauma in rats. J Neurosurg. 1998 Jun;88(6):1066-74.