Details of the Drug-Related molecule(s) Interaction Atlas

US9623028, Compound 79 Drug Info

SCHEMBL15882853; CHEMBL4093026; US9623028, Compound 79; BDBM317465; 4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)phenyl)-7H- pyrrolo[2,3-d]pyrimidin-2- ylamino)-3-methoxy-N- methylbenzamide

Cross-matching ID

PubChem CID

77846902

TTD Drug ID

DMMSHX4

General Information of Drug (ID: DMMSHX4)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Calmodulin-dependent kinase II (CAMKK2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9623028, Compound 101	DM6F7M2	N. A.	N. A.	Patented	[1]
CQ7	DMXP073	N. A.	N. A.	Patented	[1]
PMID22136433C20	DMI8217	Discovery agent	N.A.	Investigative	[2]
STO609	DMZSOG2	Discovery agent	N.A.	Investigative	[3]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Calmodulin-dependent kinase II (CAMKK2)	TTV298Y	KKCC2_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof. US9623028.
2	7,8-dichloro-1-oxo-beta-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes. J Med Chem. 2012 Jan 12;55(1):403-13.
3	STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase. J Biol Chem. 2002 May 3;277(18):15813-8.