Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMN320E)

Drug Name

A-558693 Drug Info

Synonyms

A-705239; A-705253; Calpain inhibitors (neurological disorders); Calpain inhibitors, Knoll; Calpain inhibitors (neurological disorders), Abbott

Indication

Disease Entry	ICD 11	Status	REF
Neurological disorder	6B60	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Calpain-2 (CAPN2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABT-957	DMB9N4J	Alzheimer disease	8A20	Phase 1	[2]
PMID25399719-Compound-17	DMRXKJZ	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 9	DM49FU0	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 4	DMCF6M8	N. A.	N. A.	Patented	[3]
Carboxamide derivative 7	DM8TQS4	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 7	DMTSPVF	N. A.	N. A.	Patented	[3]
Carboxamide derivative 10	DM5WMO9	N. A.	N. A.	Patented	[3]
Carboxamide derivative 11	DM1DN94	N. A.	N. A.	Patented	[3]
Carboxamide derivative 8	DM6HI34	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 10	DMYF39U	N. A.	N. A.	Patented	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2336).
2	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3	An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.