General Information of Drug (ID: DMN9KJ2)

Drug Name
Lenercept Drug Info
Synonyms Tenefuse; RsTNFR-IgG1; Ro-45-2081; TNF receptor-Ig, Roche; TNFR-IgG1 fusion protein, Roche
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Discontinued in Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMN9KJ2

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Drug(s) Targeting TNF receptor (TNFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ETX201 DMS436I Crohn disease DD70 Phase 1 [3]
BB-2275 DM6ETM8 Human immunodeficiency virus infection 1C62 Terminated [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TNF receptor (TNFR) TTZXH48 NOUNIPROTAC Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004745)
2 Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controll... Crit Care Med. 2001 Mar;29(3):503-10.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNF alpha processing in RA sy... J Clin Invest. 1996 Jun 15;97(12):2833-41.